Where will the Antichrist come from and what will he do when he arrives in Jerusalem?
The Antichrist will come from Europe, from the West. When he arrives in Jerusalem, he will go into the Temple and defile it, then immediately turn against the Jewish people, causing them to flee in an exodus. This triggers the fleeing remnant described in the passage.
Les explains that the Antichrist will come from Europe, from the West. He will go down into Jerusalem, enter the Temple, defile it, and immediately turn on the Jew. This precipitates the Exodus of the children of Israel. Les connects this to Jesus' warning to pray that the flight not be in winter or on the Sabbath, because the escaping remnant will be walking long distances, carrying goods, and it will be a miserable flight. The passage shows a cross section of society—older, working class, young marrieds with children—all included in that fleeing remnant.