Who is at the center of all of God's dealings with the human race?
The nation of Israel is at the center of all of God's dealings with the human race. The text identifies Israel as the focal point, and Jacob's trouble is described as the time when God is dealing with that nation.
Les explains that in all of God's dealing with the human race, the center of it all is the nation of Israel. He ties this to the time of Jacob's trouble, saying that is who God is dealing with. He then goes back to Deuteronomy 32:8, noting that the term "Most High" is mostly associated with the Gentile, as with Nebuchadnezzar and the Babylonians in Daniel, but the central focus remains Israel.