Why did the rulers of that age not recognize and crucify the Lord of glory knowingly?
They did not recognize Him because they did not have the wisdom of God; they possessed only the wisdom of men and the wisdom of religion. Had they known, they would never have carried out the crucifixion. They therefore acted in ignorance, not knowing the Lord of glory.
Les explains that the rulers of that age had the wisdom of men and the wisdom of religion, but they did not have the wisdom of God. Because they lacked God's wisdom, they did not know. If they had known, they would never have carried it out. Paul contrasts the wisdom of men with the wisdom of God, then quotes that eye has not seen, ear has not heard, neither has entered into the heart of man the things God has prepared for those who love Him.
Which none of the princes of this world knew: for had they known it, they would not have crucified the Lord of glory.