What changed for Adam and Eve after they left the Garden of Eden?
After leaving Eden, all circumstances changed for Adam and Eve. They had to labor by the sweat of their brow, contend with weeds and thistles, sickness and disease, war and famine, and the curse fell upon them. None of these hardships existed in the Garden, making life a wholly different set of circumstances.
Les explains that when Adam and Eve came out of the Garden, everything changed—all circumstances changed. They now had to work by the sweat of their face, or by the brow as he likes to put it. They had weeds and thistles, sickness and disease, war and famine, and the curse fell. None of that was present in the Garden, so it was a whole different set of circumstances.