Are the missiles that were once pointed at America still aimed at American targets today?
Yes. The context states that Time Magazine reported every missile ever pointed at America remains in place and still aimed at the American target. The speaker uses that report to argue Russia would strike North America first in a future invasion of Israel.
Les explains this within a scenario: if Russian leaders were preparing to invade Israel, they would recognize America as Israel’s only friend and the one nation likely to oppose them. He cites Time Magazine’s statement that every missile once pointed at America is still sitting there and still pointed at the American target. He then speculates that Russia might unload everything on North America, knocking the Western Hemisphere out of prophecy. After that initial attack, he suggests U.S. submarines with ballistic missiles would retaliate against the Russian homeland, which will destroy it. He calls this speculation and common sense, not fear-mongering.