Why were the Jews constantly trying to kill Paul?
The Jews constantly sought to kill Paul because they treated him just as he had earlier treated them, and they spoke against his message of salvation. They tried to upset his ministry, though he had no controversy with them and never lost his love for his kinsmen according to the flesh.
Les explains that the Jews treated Paul just as he had treated them earlier, so they were constantly after his life, trying to kill him one way or another. When they spoke against his message of salvation, Paul was constrained to appeal to Caesar. He had nothing to accuse his nation of, and for the hope of Israel he was bound in chains. Though they tried to upset his ministry, Paul never lost his love for his kinsmen according to the flesh. Later, Jewish leaders in Rome met with him, could not agree among themselves, and departed after Paul cited Isaiah's words about hearing but not understanding.