Can mankind be subject to the law of God according to Romans 8?
No. Romans 8 states that rebellious mankind is enmity against God and is not subject to the law of God, neither indeed can be. They are total rebels; the text means exactly what it says, so mankind cannot subject itself to God's law.
Les explains that Romans 8 describes mankind as enmity against God and total rebels. They have no fear of God before their eyes because they have no real comprehension of who God is or of the power He can employ; they ignore Him and push Him out of their thinking. Consequently, mankind is not subject to the law of God, neither indeed can be. Les notes this is hard to swallow, but it means exactly what it says. He illustrates that people may want to legislate morality to stop murder, teenage pregnancies, and drug addiction, but they cannot; the drug war cannot stop drugs until people stop wanting to use them.
Because the carnal mind is enmity against God: for it is not subject to the law of God, neither indeed can be.