What did God do to four powerful demonic beings near the Euphrates River?
God confined four powerful demonic beings who had been under Satan's rule, binding them in the area of the Euphrates River. This occurred at the time God scattered the human race at Babel or possibly later after Babylon fell to the Medes and Persians.
Les explains that all pagan mythological religions have their roots at the Tower of Babel on the Euphrates River. Evidently, at the time God scattered the human race, or maybe later after Babylon fell to the Medes and Persians, God confined four powerful demonic beings. These beings had been under Satan's rule, and they were bound in the area of the Euphrates River. Les also notes that the Euphrates is the great boundary between east and west; east of it has been predominantly pagan idolatrous religions, while west of it includes Judaism, Muhammadism, and Christianity.