What does it mean that we know Christ no more after the flesh?
It means that since Christ's death, burial, and resurrection, and the revelation of the gospel of grace, believers no longer know Christ according to the fleshly, Law-based perspective of His earthly teaching to Israel under the Law. We no longer go by the things He taught Israel under the Law.
Les explains that since the death, burial, and resurrection of Christ, and since the revelation of the gospel of the grace of God, we do not know Christ after the flesh. This means we are no longer going by the things He taught to Israel under the Law. To make it certain we are no longer under the Law, God prompted the Roman Army to destroy the temple, the priesthood was uprooted, and Israel was sent out into the nations, so there was no temptation to hang on to temple worship.
Wherefore henceforth know we no man after the flesh: yea, though we have known Christ after the flesh, yet now henceforth know we him no more.
More Questions
Why does Paul say in 2 Corinthians 5:16 that we know Christ no more after the flesh?
Paul can write that we know Christ no more after the flesh because God is separating Judaism and Christianity, so we no longer know Him according to the flesh.
Why does Paul say he no longer knows Christ after the flesh?
Because of his revelations on the road to Damascus and in Arabia, Paul no longer refers to Christ in his earthly ministry, which is what he means by knowing no man after the flesh.
Why does Paul say 'henceforth know we no man after the flesh'?
Paul says 'wherefore henceforth know we no man after the flesh' because of the work of the cross — Christ's death, burial, and resurrection — so from that point on we no longer relate to Him on the basis of the flesh.